Why do we need to donate the rarest blood types? Ro blood is essential in the treatment of sickle cell disease, which is a set of genetic blood abnormalities affecting red blood cells. Due to the disease, the demand for Ro blood type is growing by 10-15% each year, but only 2% of frequent donors have this subtype, making it very rare. You can have this subtype regardless of whether you have O, A, B or AB blood type. The Ro blood type is a subtype of the Rh-positive blood type. Hence, it is referred to as “golden blood”, as it is worth more than its weight in gold. Individuals with any blood type can accept Rhnull blood. The blood type is so uncommon that only 43 people have ever been identified with this blood type, and there are only nine donors at present. This includes the D antigen as well as 60 other antigens. This subtype is distinguished by a total absence of Rh antigens. Rhnull blood is the most uncommon blood type.
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